Daidzein, CAS# 486-66-8, is a type of isoflavone compounds manufactured through extraction from various plants and herbs, available as White fine powder. Daidzein is widely used as nutritional supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Daidzein is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Daidzein for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Daidzein could have any negative effects on these vulnerable groups. It should be safe to use Daidzein in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Daidzein for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Daidzein is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Daidzein reported up to now.
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1. Safety evaluation of daidzein in laying hens: part I. Effects on laying performance, clinical blood parameters, and organs development. [Food Chem Toxicol. 2013 May]
Author: Shi SR, Gu H, Chang LL, Wang ZY, Tong HB, Zou JM.
2. Safety evaluation of daidzein in laying hens: part II. Effects on calcium-related metabolism. [Food Chem Toxicol. 2013 May]
Author: Gu H, Shi SR, Chang LL, Tong HB, Wang ZY, Zou JM.
3. Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity. [Br J Pharmacol. 2011 Dec]
Author: Crespillo A, Alonso M, Vida M, Pavón FJ, Serrano A, Rivera P, Romero-Zerbo Y, Fernández-Llebrez P, Martínez A, Pérez-Valero V, Bermúdez-Silva FJ, Suárez J, de Fonseca FR.
4. The effect of the phytoestrogens genistein, daidzein, and equol on the growth of tamoxifen-resistant T47D/PKC alpha. [Nutr Cancer. 2007]
Author: Tonetti DA, Zhang Y, Zhao H, Lim SB, Constantinou AI.