Chrysin, CAS# 480-40-0, is a flavone manufactured through extraction from various plants, available as White powder. Chrysin is widely used as nutritional supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Chrysin is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Chrysin for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Chrysin could have any negative effects on these vulnerable groups. It should be safe to use Chrysin in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Chrysin for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Chrysin is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Chrysin reported up to now.
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1. A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer.
[Cancer Chemother Pharmacol. 2006 Feb]
Author: Tobin PJ1, Beale P, Noney L, Liddell S, Rivory LP, Clarke S.