L-Glutamine, CAS# 56-85-9, is a glutamic acid derivative manufactured through chemical synthesis from glutamate and ammonia, available as Crystalline Powder. L-Glutamine is widely used as nutritional supplements. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries.
L-glutamine intake should be limited to no more than 40mg a day. It may be involved in liver damage and sensitivity to MSG.
As L-Glutamine is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of L-Glutamine for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that L-Glutamine could have any negative effects on these vulnerable groups. It should be safe to use L-Glutamine in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of L-Glutamine for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Glutamine is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about L-Glutamine reported up to now.
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1. Risk assessment for the amino acids taurine, L-glutamine and L-arginine. [Regul Toxicol Pharmacol. 2008 Apr]
Author: Shao A, Hathcock JN.
2. L-Glutamine Supplementations Enhance Liver Glutamine-Glutathione Axis and Heat Shock Factor-1 Expression in Endurance-Exercise Trained Rats. [Int J Sport Nutr Exerc Metab. 2014 Sep 8]
Author: Petry ER, Cruzat VF, Heck TG, Homem de Bittencourt PI Jr, Tirapegui J.