L-Arginine Alpha-Ketoglutarate, CAS# 5256-76-8, is a salt of the amino acid arginine and alpha-ketoglutaric acid manufactured through chemical synthesis, available as White or light yellowish crystalline powder. L-Arginine Alpha-Ketoglutarate is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As L-Arginine Alpha-Ketoglutarate is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of L-Arginine Alpha-Ketoglutarate for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that L-Arginine Alpha-Ketoglutarate could have any negative effects on these vulnerable groups. It should be safe to use L-Arginine Alpha-Ketoglutarate in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of L-Arginine Alpha-Ketoglutarate for long period in food for newborns or pregnant.
Though L-Arginine Alpha-Ketoglutarate is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No breaking news or public health crises reported about L-Arginine Alpha-Ketoglutarate reported up to now.
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1. Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. [J Int Soc Sports Nutr. 2012 Apr 17]
Author: Wax B, Kavazis AN, Webb HE, Brown SP.
2. Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men. [Nutrition. 2006 Sep]
Author: Campbell B, Roberts M, Kerksick C, Wilborn C, Marcello B, Taylor L, Nassar E, Leutholtz B, Bowden R, Rasmussen C, Greenwood M, Kreider R.