DL-Methionine, CAS# 59-51-8, is a amino acid manufactured through fermentation, available as White Crystalline Powder. Dl-Methionine is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
It's safe to use DL-Methionine as food additives. However, high doses of DL-Methionine can cause brain damage and death.
As Dl-Methionine is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Dl-Methionine for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Dl-Methionine could have any negative effects on these vulnerable groups. It should be safe to use Dl-Methionine in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Dl-Methionine for long period in food for newborns or pregnant.
Though Dl-Methionine is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No breaking news or public health crises reported about Dl-Methionine reported up to now.
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1. Effects of different dietary protein levels and DL-methionine supplementation on hair growth and pelt quality in mink (Neovision vision). [J Anim Physiol Anim Nutr (Berl). 2013 Dec]
Author: Zhang HH, Jiang QK, Sun WL, Xu C, Cong B, Yang FH, Li GY.
2. Bioavailability of methionine hydroxy analog-calcium salt relative to DL-methionine to support nitrogen retention and growth in starter pigs. [Animal. 2012 Nov]
Author: Opapeju FO, Htoo JK, Dapoza C, Nyachoti CM.
3. Pig performance increases with the addition of DL-methionine and L-lysine to ensiled cassava leaf protein diets. [Trop Anim Health Prod. 2012 Jan]
Author: Ly NT, Ngoan le D, Verstegen MW, Hendriks WH.
4. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. [Br J Nutr. 2011 Dec]
Author: Swennen Q, Geraert PA, Mercier Y, Everaert N, Stinckens A, Willemsen H, Li Y, Decuypere E, Buyse J.
5. Effects of diets with different protein and DL-methionine levels on the growth performance and N-balance of growing minks. [J Anim Physiol Anim Nutr (Berl). 2012 Jun]
Author: Zhang HH, Li GY, Ren EJ, Xing XM, Wu Q, Yang FH.