Caffeine Anhydrous, CAS# 5743-12-4, is a plant extraction manufactured through chemical synthesis, available as White or almost white, crystalline powder (BP/EP) or silky, white or almost white, crystals. Caffeine Anhydrous is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
Caffeine can cause insomnia, nervousness and restlessness, stomach irritation, nausea and vomiting, increased heart rate and respiration, and other side effects. Caffeine can make sleep disorders in patients with acquired immunodeficiency syndrome (AIDS) worse. Larger doses might cause headache, anxiety, agitation, chest pain, and ringing in the ears.
As Caffeine Anhydrous is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Caffeine Anhydrous for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
Caffeine Anhydrous may have some affect on pregnant or breast-feeding women. We recommend consumers to consult professionals before using Caffeine Anhydrous in food of pregnant or breast-feeding women.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Caffeine Anhydrous is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Caffeine Anhydrous reported up to now.
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1. Development and validation of RP-HPLC method for simultaneous estimation of nimesulide, phenylephrine hydrochloride, chlorpheniramine maleate and caffeine anhydrous in pharmaceutical dosage form. [2012 Nov-Dec]
Author: Acta Pol Pharm