EDTA (Ethylenediaminetetraacetic Acid), CAS# 60-00-4, is a aminopolycarboxylic acid manufactured through chemical synthesis, available as Pure White Free Flowing Crystalline Powder. Edta is widely used as stabilizer in cosmetic and personal care products. .
abdominal cramps, nausea, vomiting, diarrhea, headache, low blood pressure, skin problems, and fever.
Ingestion of EDTA in large quantity may hurt our health, please follow the guideline of using EDTA: ADI 0-2.5 mg/kg bw
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that EDTA could have any negative effects on these vulnerable groups. It should be safe to use EDTA in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of EDTA for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. EDTA is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about EDTA reported up to now.
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1. Effectiveness of treatment of calcific tendinitis of the shoulder by disodium EDTA. [Arthritis Rheum. 2009 Jan 15]
Author: Cacchio A, De Blasis E, Desiati P, Spacca G, Santilli V, De Paulis F.
2. High-purity nano particles ZnS production by a simple coupling reaction process of biological reduction and chemical precipitation mediated with EDTA. [Biotechnol Prog. 2008 Sep-Oct]
Author: Xin B, Huang Q, Chen S, Tang X.
3. Effect of ovotransferrin, protamine sulfate and EDTA combination on biofilm formation by catheter-associated bacteria. [J Appl Microbiol. 2007 Mar]
Author: Yakandawala N, Gawande PV, Lovetri K, Madhyastha S.
4. The effect of clodronate on the integrity and viability of rat small intestine in vitro-a comparison with EDTA. [Biol Pharm Bull. 2005 Jul]
Author: Zakelj S, Vadnjal L, Kristl A.