Sodium Bicarbonate (Baking Soda), CAS# 144-55-8, is a sodium salt of carbonate manufactured through chemical synthesis, available as white crystalline powder. Sodium Bicarbonate is widely used as leavening agent. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E500.
No significant side effects reported.
As Sodium Bicarbonate is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Sodium Bicarbonate for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Sodium Bicarbonate could have any negative effects on these vulnerable groups. It should be safe to use Sodium Bicarbonate in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Sodium Bicarbonate for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Bicarbonate is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Sodium Bicarbonate reported up to now.
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1. Sodium acetate as a replacement for sodium bicarbonate in medical toxicology: a review. [J Med Toxicol. 2013 Sep]
Author: Neavyn MJ, Boyer EW, Bird SB, Babu KM.
2. Oral prostaglandin e1 in combination with sodium bicarbonate and normal saline in the prevention of contrast-induced nephropathy: a pilot study. [Int J Angiol. 2011 Dec]
Author: Franz RW, Hinze SS, Knapp ED, Jenkins JJ 2nd.
3. Effects of caffeine, sodium bicarbonate, and their combined ingestion on high-intensity cycling performance. [Int J Sport Nutr Exerc Metab. 2012 Jun]
Author: Kilding AE, Overton C, Gleave J.
4. Dimethyl sulfoxide and sodium bicarbonate in the treatment of refractory cancer pain. [J Pain Palliat Care Pharmacother. 2011]
Author: Hoang BX, Tran DM, Tran HQ, Nguyen PT, Pham TD, Dang HV, Ha TV, Tran HD, Hoang C, Luong KN, Shaw DG.