Neotame, CAS# 165450-17-9, is a artificial sweetener manufactured through chemical synthesis, available as white powder with no odor. Neotame is widely used as sweetener as it is between 7,000 and 13,000 times sweeter than sucrose. It is widely accepted as safe food additive in many countries with E number E961.
No significant side effects of neotame are reported.
Ingestion of Neotame in large quantity may hurt our health, please follow the guideline of using Neotame: ADI 0-2 mg/kg bw
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Neotame could have any negative effects on these vulnerable groups. It should be safe to use Neotame in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Neotame for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Neotame is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Neotame reported up to now.
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1. Determination of neotame in beverages, cakes and preserved fruits by column-switching high-performance liquid chromatography. [Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Sep]
Author: Yang D, Chen B.
2. Long-term food consumption and body weight changes in neotame safety studies are consistent with the allometric relationship observed for other sweeteners and during dietary restrictions. [Regul Toxicol Pharmacol. 2003 Oct]
Author: Flamm WG, Blackburn GL, Comer CP, Mayhew DA, Stargel WW.