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 Xylitol Side Effects

    Xylitol Side Effects

    by Daniel Peng 2014-09-04

    Xylitol, CAS# 87-99-0, is a polyalcohol or sugar alcohol manufactured through extraction and isolation from hardwoods or corncobs, available as WHITE CRYSTALS. Xylitol is widely used as sweetener. It is widely accepted as safe food additive in many countries with E number E967.

    General Side Effects

    1. Xylitol can cause diarrhea and intestinal gas when ingusted in large amount. 2. There is some concern that using xylitol in extremely high doses for long periods of time can cause tumors.


    * Report new side effects to us by sending email to foodchemmis08@foodchem.cn. Our expert will review it and respond soon.

    Suggested Dosage

    As Xylitol is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Xylitol for long period.


    * ADI: Acceptable Daily Intake
    * MTDI: maximum tolerable daily intake
    * Data source: JECFA Database of WHO

    Special Groups Precaution

    Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
    There is no evidence that Xylitol could have any negative effects on these vulnerable groups. It should be safe to use Xylitol in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Xylitol for long period in food for newborns or pregnant.

    GRAS Affirmation: Yes

    Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Xylitol is considered safe by FDA according to existing data and granted GRAS status.

    Xylitol in News

    1. Sugarless Gum Containing Xylitol is safe to Cats
    Reference: http://www.catster.com/lifestyle/cat-health-sugarless-gum-xylitol-toxic-harmful-cats-ask-a-vet

    Related Research

    1. Xylitol; A review on Bio-production, Application, Health Benefits and Related Safety Issues. [Crit Rev Food Sci Nutr. 2013 Oct]
    Author: Ur-Rehman S, Mushtaq Z, Zahoor T, Jamil A, Anjum Murtaza M.

    2. Xylitol toxicosis in dogs. [Vet Clin North Am Small Anim Pract. 2012 Mar]
    Author: Murphy LA, Coleman AE.



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