Sorbitol, CAS# 50-70-4, is a sugar alcohol manufactured through chemical synthesis, available as WHITE CRYSTALLINE GRANULE OR POWDER. Sorbitol is widely used as sweetener. It is widely accepted as safe food additive in many countries with E number E420.
1. Sorbitol can cause bloating, gas and diarrhea. 2. Sorbitol can pose laxative effect when ingusted in large amount.
As Sorbitol is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Sorbitol for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Sorbitol could have any negative effects on these vulnerable groups. It should be safe to use Sorbitol in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Sorbitol for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sorbitol is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Sorbitol reported up to now.
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1. Comparative study--efficacy, safety and compliance of intravenous iron sucrose and intramuscular iron sorbitol in iron deficiency anemia of pregnancy. [J Pak Med Assoc. 2002 Sep]
Author: Wali A, Mushtaq A, Nilofer.
2. Pharmacokinetics, pharmacodynamics, tolerability, and safety of a novel sorbitol dehydrogenase inhibitor in healthy participants. [J Clin Pharmacol. 2010 May]
Author: Landau Z, Novotny MJ, Preston GM, Wright K, Freeman T, Dai H, Thompson J, Oates PJ, Calle RA.