Methyl Salicylate, CAS# 119-36-8, is a organic ester manufactured through esterifying salicylic acid with methanol, available as Colorless to slight yellow transparent oily liquid. Methyl Salicylate is widely used as flavoring agent or fragrance. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries.
No significant side effects reported.
Ingestion of Methyl Salicylate in large quantity may hurt our health, please follow the guideline of using Methyl Salicylate: ADI 0-10 mg/kg bw
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Methyl Salicylate could have any negative effects on these vulnerable groups. It should be safe to use Methyl Salicylate in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Methyl Salicylate for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Methyl Salicylate is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Methyl Salicylate reported up to now.
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1. Role of Methyl Salicylate on Oviposition Deterrence in Arabidopsis thaliana. [J Chem Ecol. 2014 Jul]
Author: Groux R, Hilfiker O, Gouhier-Darimont C, Peñaflor MF, Erb M, Reymond P.
2. Hair analysis as a useful procedure for detection of vapour exposure to chemical warfare agents: simulation of sulphur mustard with methyl salicylate. [Drug Test Anal. 2014 Jun]
Author: Spiandore M, Piram A, Lacoste A, Josse D, Doumenq P.
3. New Insights into the Dual Fluorescence of Methyl Salicylate: Effects of Intermolecular Hydrogen Bonding and Solvation. [J Phys Chem B. 2014 Apr 17]
Author: Zhou P, Hoffmann MR, Han K, He G.
4. Highly sensitive electrochemical detection of methyl salicylate using electroactive gold nanoparticles. [Analyst. 2013 Nov 7]
Author: Umasankar Y, Ramasamy RP.