D-Aspartic Acid, CAS# 1783-96-6, is a proteinogenic amino acid manufactured through fermentation, available as White Crystals or crystalline powder. D-Aspartic Acid is widely used as nutritional supplements. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries.
No significant side effects reported.
As D-Aspartic Acid is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of D-Aspartic Acid for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that D-Aspartic Acid could have any negative effects on these vulnerable groups. It should be safe to use D-Aspartic Acid in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of D-Aspartic Acid for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. D-Aspartic Acid is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about D-Aspartic Acid reported up to now.
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1. D-aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men. [Nutr Res. 2013 Oct]
Author: Willoughby DS, Leutholtz B.
2. Decreased levels of free D-aspartic acid in the forebrain of serine racemase (Srr) knock-out mice. [Neurochem Int. 2013 May]
Author: Horio M, Ishima T, Fujita Y, Inoue R, Mori H, Hashimoto K.
3. Gender differences in D-aspartic acid content in skull bone. [Hiroshima J Med Sci. 2012 Dec]
Author: Torikoshi-Hatano A, Namera A, Shiraishi H, Arima Y, Toubou H, Ezaki J, Morikawa M, Nagao M.
4. D-Aspartic acid implication in the modulation of frog brain sex steroid levels. [Gen Comp Endocrinol. 2013 Jan 15]
Author: Santillo A, Pinelli C, Burrone L, Chieffi Baccari G, Di Fiore MM.