L-Tyrosine, CAS# 60-18-4, is a amino acid manufactured through fermentation, available as White crystals or crystalline tasteless powder. L-Tyrosine is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported. L-Tyrosine can cause nausea, headache, fatigue, heartburn, and joint pain in specific groups of individuals.
As L-Tyrosine is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of L-Tyrosine for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that L-Tyrosine could have any negative effects on these vulnerable groups. It should be safe to use L-Tyrosine in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of L-Tyrosine for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Tyrosine is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about L-Tyrosine reported up to now.
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1. Review of L-tyrosine confirming its safe human use as an adjuvant. [J Appl Toxicol. 2002 Sep-Oct]
Author: Baldrick P, Richardson D, Wheeler AW.
2. Administration of supplemental L-tyrosine with phenelzine: a clinical literature review. [Clin Pharmacol. 2014 Jul 22]
Author: Hinz M, Stein A, Cole T, Ryan P.
3. Novel synthesis of gold nanoclusters templated with l-tyrosine for selective analyzing tyrosinase. [Anal Chim Acta. 2014 Aug 20]
Author: Yang X, Luo Y, Zhuo Y, Feng Y, Zhu S.
4. Evaluation of Various Factors Affecting Bioconversion of l-Tyrosine to l-DOPA by Yeast Yarrowia lipolytica-NCIM 3450 Using Response Surface Methodology. [Nat Prod Bioprospect. 2014]
Author: Gurme ST, Surwase SN, Patil SA, Jadhav JP.