Succinic Acid, CAS# 110-15-6, is a dicarboxylic acid manufactured through hydrogenation of maleic acid, oxidation of 1,4-butanediol or carbonylation of ethylene glycol, available as White Crystal Powder. Succinic Acid is widely used as acidity regulator. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E363.
diarrhea, constipation, stomach upset, nausea and darkened or green stools.
As Succinic Acid is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Succinic Acid for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Succinic Acid could have any negative effects on these vulnerable groups. It should be safe to use Succinic Acid in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Succinic Acid for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Succinic Acid is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Succinic Acid reported up to now.
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1. Conjugation of succinic acid to non-ionogenic amphiphilic polymers modulates their interaction with cell plasma membrane and reduces cytotoxic activity.
[Colloids Surf B Biointerfaces. 2013 Sep 1]
Author: Bondar OV, Sagitova AV, Badeev YV, Shtyrlin YG, Abdullin TI.
2. 99mTechnetium-dimercapto-succinic acid renal scan in the evaluation of potential long-term renal parenchymal damage associated with extracorporeal shock wave lithotripsy in children. [J Urol. 1998 Feb]
Author: Lottmann HB, Archambaud F, Hellal B, Pageyral BM, Cendron M.