Microcrystalline Cellulose, CAS# 9004-34-6, is a term for refined wood pulp manufactured through plant fibre hydrolysis, available as fine white or almost white odorless powder. Microcrystalline Cellulose is widely used as emulsifiers. It is widely accepted as safe food additive in many countries with E number E460.
1. Microcrystalline Cellulose can cause moderate to severe bowel movement when ingusted in large amount. 2. Microcrystalline Cellulose can cause loss of energy and weight when ingusted in large amount as it can not be absorbed and reduces the absorption of other dietary nutrients. 3. Microcrystalline Cellulose can cause allergic reaction in some individuals, the typical reaction is diarrhoea or gas problems.
As Microcrystalline Cellulose is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Microcrystalline Cellulose for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Microcrystalline Cellulose could have any negative effects on these vulnerable groups. It should be safe to use Microcrystalline Cellulose in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Microcrystalline Cellulose for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Microcrystalline Cellulose is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Microcrystalline Cellulose reported up to now.
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1. Microcrystalline cellulose membrane for re-epithelisation of chronic leg wounds: a prospective open study. [Int Wound J. 2010 Dec]
Author: Ricci EB, Cassino R, Di Campli C.
2. Biohydrogen generation by mesophilic anaerobic fermentation of microcrystalline cellulose. [Biotechnol Bioeng. 2001 Aug]
Author: Lay JJ.
3. Qualitative investigation of uptake of fine particle size microcrystalline cellulose following oral administration in rats. [J Anat. 1996 Dec]
Author: Kotkoskie LA, Butt MT, Selinger E, Freeman C, Weiner ML.