Butylated HydroxyToluene, CAS# 128-37-0, is a lipophilic organic compound manufactured through chemical synthesis, available as white crystals or crystalline powder. Butylated Hydroxy Toluene is widely used as antioxidants. It is widely accepted as safe food additive in many countries with E number E321.
No significant side effects reported.
Ingestion of Butylated Hydroxy Toluene in large quantity may hurt our health, please follow the guideline of using Butylated Hydroxy Toluene: ADI 0-0.3 mg/kg bw
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Butylated Hydroxy Toluene could have any negative effects on these vulnerable groups. It should be safe to use Butylated Hydroxy Toluene in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Butylated Hydroxy Toluene for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Butylated Hydroxy Toluene is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Butylated Hydroxy Toluene reported up to now.
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1. FT-IR, FT-Raman spectra, density functional computations of the vibrational spectra and molecular geometry of butylated hydroxy toluene. [Spectrochim Acta A Mol Biomol Spectrosc. 2011 Aug]
Author: Babu PC, Sundaraganesan N, Dereli Ö, Türkkan E.
2. Effect of a polyherbal formulation, Ambrex, on butylated hydroxy toluene (BHT) induced toxicity in rats. [Indian J Exp Biol. 2003 Nov]
Author: Devi RS, Narayan S, Mohan KV, Sabitha KE, Devi CS.
3. Induction of type 1 programmed cell death in U937 cells by the antioxidant, butylated hydroxy-toluene or the free radical spin trap, NTBN. [Leuk Res. 1999 Jul]
Author: Anderson KM, Ou D, Wu YB, Jajeh A, Harris JE.
4. Pulmonary phospholipid changes induced by butylated hydroxy toluene, an antioxidant, in rats. [Indian J Exp Biol. 1995 Oct]
Author: Tamizhselvi R, Samikkannu T, Niranjali S.
5. Allopurinol promotes and butylated hydroxy toluene prevents sugar-induced cataractogenesis. [Biochem Biophys Res Commun. 1990 May 16]
Author: Ansari NH, Srivastava SK.