Tertiary Butylhydroquinone(TBHQ), CAS# 1948-33-0, is a aromatic organic compound manufactured through chemical synthesis, available as white to off-white crystallized powder. Tertiary Butylhydroquinone is widely used as antioxidants. It is widely accepted as safe food additive in many countries with E number E319.
No significant side effects reported. Large doses of Tertiary Butylhydroquinone can pose toxic effect.
Ingestion of Tertiary Butylhydroquinone in large quantity may hurt our health, please follow the guideline of using Tertiary Butylhydroquinone: ADI 0-0.7 mg/kg bw
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Tertiary Butylhydroquinone could have any negative effects on these vulnerable groups. It should be safe to use Tertiary Butylhydroquinone in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Tertiary Butylhydroquinone for long period in food for newborns or pregnant.
Though Tertiary Butylhydroquinone is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No breaking news or public health crises reported about Tertiary Butylhydroquinone reported up to now.
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1. Tertiary-butylhydroquinone upregulates expression of ATP-binding cassette transporter A1 via nuclear factor E2-related factor 2/heme oxygenase-1 signaling in THP-1 macrophage-derived foam cells. [Circ J. 2013]
Author: Lu Q, Tang SL, Liu XY, Zhao GJ, Ouyang XP, Lv YC, He PP, Yao F, Chen WJ, Tang YY, Zhang M, Zhang DW, Yin K, Tang CK.
2. Oxidative stability of virgin olive oil as affected by the bene unsaponifiable matters and tertiary-butylhydroquinone. [J Food Sci. 2012 Jun]
Author: Farhoosh R, Haddad Khodaparast MH, Sharif A, Zamani-Ghalehshahi A, Hoseini-Yazdi SZ.
3. Determination of tertiary-butylhydroquinone and its metabolites in rat serum by liquid chromatography-ion trap mass spectrometry. [Lipids. 2008 Mar]
Author: Huang W, Gu Y, Niu H.
4. Allergic contact dermatitis from tertiary-butylhydroquinone and Laureth 12 in a hair dye. [Contact Dermatitis. 2007 Feb]
Author: Field S, Hazelwood E, Bourke B, Bourke JF.
5. Allergic contact dermatitis from tertiary-butylhydroquinone (TBHQ) in a vegetable hydraulic oil. [Contact Dermatitis. 2000 Nov]
Author: Aalto-Korte K.