L-Glutamic Acid, CAS# 56-86-0, is a amino acid manufactured through fermentation, available as A white crystalline or crystammine powder acid taste and slightly agreeable.. L-Glutamic Acid is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported. L-Glutamic Acid can cause allergic reactions known as "Chinese restaurant syndrome" in specific groups of individuals.
As L-Glutamic Acid is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of L-Glutamic Acid for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
L-Glutamic Acid may have some affect on Children, age 3 to 18. We recommend consumers to consult professionals before using L-Glutamic Acid in food of Children, age 3 to 18.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. L-Glutamic Acid is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about L-Glutamic Acid reported up to now.
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1. Resolution and isolation of enantiomers of (±)-isoxsuprine using thin silica gel layers impregnated with l-glutamic acid, comparison of separation of its diastereomers prepared with chiral derivatizing reagents having l-amino acids as chiral auxiliaries. [Biomed Chromatogr. 2014 Jul 7]
Author: Bhushan R, Nagar H.
2. The prevention effect of poly (L-glutamic acid)/chitosan on spinal epidural fibrosis and peridural adhesion in the post-laminectomy rabbit model. [Eur Spine J. 2014 Jul 8]
Author: Li C, Wang H, Liu H, Yin J, Cui L, Chen Z.
3. Stereocontrolled synthesis of 5-azaspiro[2.3]hexane derivatives as conformationally "frozen" analogues of L-glutamic acid. [Beilstein J Org Chem. 2014 May 14]
Author: Bechi B, Amantini D, Tintori C, Botta M, Fabio Rd.
4. Comparison of neurotropic effects of L-glutamic acid and its new derivative β-phenylglutamic acid hydrochloride (RGPU-135, glutarone). [Bull Exp Biol Med. 2014 Apr]
Author: Tyurenkov IN, Bagmetova VV, Chernysheva YV, Merkushenkova OV.
5. Enzymatic production of α-ketoglutaric acid from l-glutamic acid via l-glutamate oxidase. [J Biotechnol. 2014 Jun 10]
Author: Niu P, Dong X, Wang Y, Liu L.