Synephrine, CAS# 34520, is a Plant extracts manufactured through plant extraction, available as Light-Brown Fine powder. Synephrine is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Synephrine Side Effects is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Synephrine Side Effects for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Synephrine Side Effects could have any negative effects on these vulnerable groups. It should be safe to use Synephrine Side Effects in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Synephrine Side Effects for long period in food for newborns or pregnant.
Though Synephrine Side Effects is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Synephrine Side Effects reported up to now.
1. The safety of Citrus aurantium (bitter orange) and its primary protoalkaloid p-synephrine. [Phytother Res. 2011 Oct]
Author: Stohs SJ, Preuss HG, Shara M.
2. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update. [Obes Rev. 2006 Feb]
Author: Haaz S, Fontaine KR, Cutter G, Limdi N, Perumean-Chaney S, Allison DB.
3. Seville (sour) orange juice: synephrine content and cardiovascular effects in normotensive adults. [J Clin Pharmacol. 2001 Oct]
Author: Penzak SR, Jann MW, Cold JA, Hon YY, Desai HD, Gurley BJ.
4. Third place--Resident Clinical Science Award 1990. The in vivo and in vitro effect of phenylephrine (Neo Synephrine) on nasal ciliary beat frequency and mucociliary transport. [Otolaryngol Head Neck Surg. 1990 Oct]
Author: Phillips PP, McCaffrey TV, Kern EB.