Hesperidin, CAS# 520-26-3, is a Plant extracts manufactured through plant extraction, available as Light yellow fine powder . Hesperidin is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Hesperidin Side Effects is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Hesperidin Side Effects for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Hesperidin Side Effects could have any negative effects on these vulnerable groups. It should be safe to use Hesperidin Side Effects in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Hesperidin Side Effects for long period in food for newborns or pregnant.
Though Hesperidin Side Effects is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Hesperidin Side Effects reported up to now.
1. Hesperidin methyl chalcone inhibits oxidative stress and inflammation in a mouse model of ultraviolet B irradiation-induced skin damage. [J Photochem Photobiol B. 2015 Jul]
Author: Martinez RM, Pinho-Ribeiro FA, Steffen VS, Caviglione CV, Vignoli JA, Baracat MM, Georgetti SR, Verri WA Jr, Casagrande R.
2. Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial. [Tech Coloproctol. 2015 Jun]
Author: Giannini I, Amato A, Basso L, Tricomi N, Marranci M, Pecorella G, Tafuri S, Pennisi D, Altomare DF.
3. Hesperidin, a citrus bioflavonoid, ameliorates genotoxicity-induced by diazinon in human blood lymphocytes. [Drug Res (Stuttg). 2015 Feb]
Author: Shokrzadeh M, Ahmadi A, Ramezaninejhad S, Shadboorestan A.
4. Improvement of dissolution and absorption properties of poorly water-soluble drug by preparing spray-dried powders with alpha-glucosyl hesperidin. [Int J Pharm. 2010 Jun 15]
Author: Uchiyama H, Tozuka Y, Imono M, Takeuchi H.