Astragaloside IV, CAS# 84687-43-4, is a Plant extracts manufactured through plant extraction, available as Yellow brown fine powder. Astragaloside Iv is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
As Astragaloside IV is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Astragaloside IV for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Astragaloside IV could have any negative effects on these vulnerable groups. It should be safe to use Astragaloside IV in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Astragaloside IV for long period in food for newborns or pregnant.
Though Astragaloside IV is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Astragaloside IV reported up to now.
1. Astragaloside IV inhibited the activity of CYP1A2 in liver microsomes and influenced theophylline pharmacokinetics in rats. [J Pharm Pharmacol. 2013 Jan]
Author: Zhang YH, Zhang YJ, Guo YL, Li WJ, Yu C.
2. [Inhibitory effects of astragaloside IV on cytochrome P450 enzyme of rat liver microsomes]. [Zhongguo Zhong Yao Za Zhi. 2012 Jan]
Author: Shan W, Zhang Y, Zhu J, Shao Q, Fan X.