Rhodiola Rosea Extract, CAS# 97404-52-9, is a Plant extracts manufactured through plant extraction, available as brown fine powder. Rhodiola Rosea Extract is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
As Rhodiola Rosea Extract is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Rhodiola Rosea Extract for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Rhodiola Rosea Extract could have any negative effects on these vulnerable groups. It should be safe to use Rhodiola Rosea Extract in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Rhodiola Rosea Extract for long period in food for newborns or pregnant.
Though Rhodiola Rosea Extract is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Rhodiola Rosea Extract reported up to now.
1. Synergistic interactions between the antinociceptive effect of Rhodiola rosea extract and B vitamins in the mouse formalin test. [Phytomedicine. 2013 Nov 15]
Author: Montiel-Ruiz RM, González-Trujano ME, Déciga-Campos M.
2. [Evaluating adaptogenic properties of Rhodiola rosea extract in human mononuclear cell culture and rat tissues]. [Eksp Klin Farmakol. 2013]
Author: Andreeva LI, Boĭkova AA, Nikiforova DV.
3. Therapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms--results of an open-label study. [Phytother Res. 2012 Aug]
Author: Edwards D, Heufelder A, Zimmermann A.
4. Rhodiola rosea extract protects human cortical neurons against glutamate and hydrogen peroxide-induced cell death through reduction in the accumulation of intracellular calcium. [Phytother Res. 2012 Jun]
Author: Palumbo DR, Occhiuto F, Spadaro F, Circosta C.
5. Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating. [Physiol Behav. 2010 Dec 2]
Author: Cifani C, Micioni Di B MV, Vitale G, Ruggieri V, Ciccocioppo R, Massi M.