Bilberry Anthocyanins, CAS# 11029-12-2, is a Plant extracts manufactured through plant extraction, available as Dark-violet fine powder. Bilberry Anthocyanins is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
severe stomach/abdominal pain.Stomach upset or diarrhea may occur with very large doses.
As Bilberry Anthocyanins is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Bilberry Anthocyanins for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Bilberry Anthocyanins could have any negative effects on these vulnerable groups. It should be safe to use Bilberry Anthocyanins in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Bilberry Anthocyanins for long period in food for newborns or pregnant.
Though Bilberry Anthocyanins is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Bilberry Anthocyanins reported up to now.
1. Practical application of flavonoid-poor menu meals to the study of the bioavailability of bilberry anthocyanins in human subjects. [Biosci Biotechnol Biochem. 2014 Oct]
Author: Sakakibara H, Ichikawa Y, Tajima S, Makino Y, Wakasugi Y, Shimoi K, Kobayashi S, Kumazawa S, Goda T.
2. Bilberry anthocyanins neutralize the cytotoxicity of co-chaperonin GroES fibrillation intermediates. [Biochemistry. 2013 Dec 23]
Author: Iwasa H, Kameda H, Fukui N, Yoshida S, Hongo K, Mizobata T, Kobayashi S, Kawata Y.
3. Modulation of Nrf2-dependent gene transcription by bilberry anthocyanins in vivo. [Mol Nutr Food Res. 2013 Mar]
Author: Kropat C, Mueller D, Boettler U, Zimmermann K, Heiss EH, Dirsch VM, Rogoll D, Melcher R, Richling E, Marko D.
4. Ginkgo biloba extract and bilberry anthocyanins improve visual function in patients with normal tension glaucoma. [J Med Food. 2012 Sep]
Author: Shim SH, Kim JM, Choi CY, Kim CY, Park KH.
5. Acute cardioprotective and cardiotoxic effects of bilberry anthocyanins in ischemia-reperfusion injury: beyond concentration-dependent antioxidant activity. [Cardiovasc Toxicol. 2010 Dec]
Author: Ziberna L, Lunder M, Moze S, Vanzo A, Tramer F, Passamonti S, Drevensek G.