Tricalcium Phosphate, CAS# 7758-87-4, is a calcium salt of phosphoric acid manufactured through chemical synthesis, available as WHITE POWDER. Tricalcium Phosphate is widely used as nutrition supplements and anticaking agent. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E341.
contact with the substance directly has led to reports of nausea, a loss of appetite, vomiting, constipation, dry mouth and increased thirst and urination.
As Tricalcium Phosphate is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Tricalcium Phosphate for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Tricalcium Phosphate could have any negative effects on these vulnerable groups. It should be safe to use Tricalcium Phosphate in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Tricalcium Phosphate for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Tricalcium Phosphate is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Tricalcium Phosphate reported up to now.
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1. Tailor-made tricalcium phosphate bone implant directly fabricated by a three-dimensional ink-jet printer. [J Artif Organs. 2006]
Author: Igawa K, Mochizuki M, Sugimori O, Shimizu K, Yamazawa K, Kawaguchi H, Nakamura K, Takato T, Nishimura R, Suzuki S, Anzai M, Chung UI, Sasaki N.
2. The bacterial inhibitory ability and in vivo drug release pattern of a new drug delivery system: ciprofloxacine/tricalcium phosphate delivery capsule. [J Tongji Med Univ. 1998]
Author: Zheng Q, Wu H, Du J, Li S, Yan Y.
3. Granular tricalcium phosphate grafting of cavitary lesions in human bone. [Clin Orthop Relat Res. 1994 Sep]
Author: Nicholas RW, Lange TA.