Sodium Dehydroacetate, CAS# 4418-26-2, is a sodium salt of dehydroacetic acid manufactured through chemical synthesis, available as White or nearly white powder. Sodium Dehydroacetate is widely used as preservative as it poses antimicrobial effect. It is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E266.
No significant side effects reported.
As Sodium Dehydroacetate is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Sodium Dehydroacetate for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Sodium Dehydroacetate could have any negative effects on these vulnerable groups. It should be safe to use Sodium Dehydroacetate in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Sodium Dehydroacetate for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Sodium Dehydroacetate is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Sodium Dehydroacetate reported up to now.
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1. Sodium dehydroacetate: an emerging allergen. [Dermatitis. 2012 Sep-Oct]
Author: Foti C, Antelmi A, Guida S, Romita P, Bonamonte D.
2. Allergic contact dermatitis caused by sodium dehydroacetate, not hyaluronic acid, in Ialuset® cream. [Contact Dermatitis. 2011 Dec]
Author: Milpied B, Collet E, Genillier N, Vigan M.
3. [Analysis of preservatives used in cosmetic products: salicylic acid, sodium benzoate, sodium dehydroacetate, potassium sorbate, phenoxyethanol, and parabens]. [Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2010]
Author: Ikarashi Y, Uchino T, Nishimura T.
4. Anticoagulant effect of sodium dehydroacetate (DHA-S) in rats. [J Appl Toxicol. 2008 May]
Author: Sakaguchi Y, Suga S, Oshida K, Miyamoto-Kuramitsu K, Ueda K, Miyamoto Y.