Calcium Gluconate, CAS# 299-28-5, is a mineral supplement manufactured through chemical synthesis, available as White crystal or granular powder. Calcium Gluconate is widely used as nutritional supplements. It is widely accepted as safe food additive in many countries with E number E578.
No significant side effects reported.
As Calcium Gluconate is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Calcium Gluconate for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Calcium Gluconate could have any negative effects on these vulnerable groups. It should be safe to use Calcium Gluconate in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Calcium Gluconate for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Calcium Gluconate is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Calcium Gluconate reported up to now.
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1. Physical Compatibility of Sodium Glycerophosphate and Calcium Gluconate in Pediatric Parenteral Nutrition Solutions. [JPEN J Parenter Enteral Nutr. 2014 Apr 2]
Author: Mackay M, Anderson C.
2. Calcium gluconate infusion is as effective as the vascular endothelial growth factor antagonist cabergoline for the prevention of ovarian hyperstimulation syndrome. [J Hum Reprod Sci. 2013 Oct]
Author: Naredi N, Karunakaran S.
3. Protective effects of calcium gluconate on osteoarthritis induced by anterior cruciate ligament transection and partial medial meniscectomy in Sprague-Dawley rats. [J Orthop Surg Res. 2014 Mar 7]
Author: Kang SJ, Kim JW, Kim KY, Ku SK, Lee YJ.
4. Clinical arterial infusion of calcium gluconate: the preferred method for treating hydrofluoric acid burns of distal human limbs. [Int J Occup Med Environ Health. 2014 Jan]
Author: Zhang Y, Ni L, Wang X, Jiang R, Liu L, Ye C, Xia W, Han C.
5. The clinical effectiveness of the intravenous infusion of calcium gluconate for treatment of hydrofluoric acid burn of distal limbs. [Burns. 2014 Jun]
Author: Zhang Y, Wang X, Ye C, Liu L, Jiang R, Ni L, Xia W, Han C.