Betulin, CAS# 473-98-3, is a Plant extracts manufactured through plant extraction, available as White Powder . Betulin is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Betulin Side Effects is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Betulin Side Effects for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Betulin Side Effects could have any negative effects on these vulnerable groups. It should be safe to use Betulin Side Effects in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Betulin Side Effects for long period in food for newborns or pregnant.
Though Betulin Side Effects is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Betulin Side Effects reported up to now.
1. Samvisterin, a new natural antiplasmodial betulin derivative From Uapaca paludosa (Euphorbiaceae). [J Ethnopharmacol. 2015 Jul 17. pii]
Author: Banzouzi JT, Njomnang Soh P, Ramos S, Toto P, Cavé A, Hemez J, Benoit-Vical F.
2. New composites of betulin esters with arabinogalactan as highly potent anti-cancer agents. [Nat Prod Res. 2015 Jul 13]
Author: Shakhtshneider TP, Kuznetsova SA, Zamay AS, Zamay TN, Spivak EA, Mikhailenko MA, Malyar YN, Kuznetsov BN, Chesnokov NV, Boldyrev VV.
3. Induction of apoptotic cell death by betulin in multidrug-resistant human renal carcinoma cells. [Oncol Rep. 2015 Aug]
Author: Yim NH, Jung YP, Kim A, Kim T, Ma JY.
4. The new esters derivatives of betulin and betulinic acid in epidermoid squamous carcinoma treatment - In vitro studies. [Biomed Pharmacother. 2015 May]
Author: Drąg-Zalesińska M, Wysocka T, Borska S, Drąg M, Poręba M, Choromańska A, Kulbacka J, Saczko J.