Icariin, CAS# 489-32-7, is a Plant extracts manufactured through plant extraction, available as Light yellow powder. Icariin is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Icariin Side Effects is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Icariin Side Effects for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Icariin Side Effects could have any negative effects on these vulnerable groups. It should be safe to use Icariin Side Effects in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Icariin Side Effects for long period in food for newborns or pregnant.
Though Icariin Side Effects is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Icariin Side Effects reported up to now.
1. Icariin, a natural flavonol glycoside, extends healthspan in mice. [Exp Gerontol. 2015 Jul 2]
Author: Zhang SQ, Cai WJ, Huang JH, Wu B, Xia SJ, Chen XL, Zhang XM, Shen ZY.
2. Icariin: a potential promoting compound for cartilage tissue engineering. [Osteoarthritis Cartilage. 2012 Dec]
Author: Li D, Yuan T, Zhang X, Xiao Y, Wang R, Fan Y, Zhang X.
3. Icariin promotes extracellular matrix synthesis and gene expression of chondrocytes in vitro. [Phytother Res. 2012 Sep]
Author: Zhang L, Zhang X, Li KF, Li DX, Xiao YM, Fan YJ, Zhang XD.
4. Icariin protects murine chondrocytes from lipopolysaccharide-induced inflammatory responses and extracellular matrix degradation. [Nutr Res. 2010 Jan]
Author: Liu MH, Sun JS, Tsai SW, Sheu SY, Chen MH.