Epimedium Extract, CAS# 489-32-7, is a Plant extracts manufactured through plant extraction, available as Brown yellow powder. Epimedium Extract is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
As Epimedium Extract is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Epimedium Extract for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Epimedium Extract could have any negative effects on these vulnerable groups. It should be safe to use Epimedium Extract in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Epimedium Extract for long period in food for newborns or pregnant.
Though Epimedium Extract is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Epimedium Extract reported up to now.
1. Epimedium extract promotes peripheral nerve regeneration in rats. [Evid Based Complement Alternat Med. 2013]
Author: Kou Y, Wang Z, Wu Z, Zhang P, Zhang Y, Yin X, Wong X, Qiu G, Jiang B.
2. [Effect of Epimedium extract on osteoprotegerin and RANKL mRNA expressions in glucocorticoid-induced femoral head necrosis in rats]. [Nan Fang Yi Ke Da Xue Xue Bao. 2011 Oct]
Author: Wang JZ, Gao HY, Wang KZ, Zhou RX, Li XD, Guo J, Lv HC.
3. Pharmacokinetics of prenylflavonoids and correlations with the dynamics of estrogen action in sera following ingestion of a standardized Epimedium extract. [J Pharm Biomed Anal. 2009 Sep 8]
Author: Wong SP, Shen P, Lee L, Li J, Yong EL.
4. [Research on quality of Epimedium extract in market]. [Zhongguo Zhong Yao Za Zhi. 2007 Sep]
Author: Peng YD, Huang WH, Guo BL.