Saponins, CAS# 8047-15-2, is a Plant extracts manufactured through plant extraction, available as brown fine powder. Saponins is widely used as nutrition supplements. It is widely accepted as safe food additive in many countries.
No significant side effects reported.
As Saponins Side Effects is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Saponins Side Effects for long period.
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Saponins Side Effects could have any negative effects on these vulnerable groups. It should be safe to use Saponins Side Effects in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Saponins Side Effects for long period in food for newborns or pregnant.
Though Saponins Side Effects is not on FDA's GRAS exemption list, it's still widely accepted as safe food additive in many countries including USA with specific limit on dosage.
No health issues about Saponins Side Effects reported up to now.
1. [Study on protective effect of total saponins of Panax japonicus on LPS-induced RAW264. 7 cell inflammation through NF-kappaB pathway]. [Zhongguo Zhong Yao Za Zhi. 2014 Jun]
Author: Dai YW, Yuan D, Wan JZ, Zhang CC, Liu CQ, Wang T.
2. Combination of autologous transplantation of G-CSF-mobilized peripheral blood mononuclear cells and Panax notoginseng saponins in the treatment of unreconstructable critical limb ischemia. [Ann Vasc Surg. 2014 Aug]
Author: Wang X, Jiang L, Wang X, Yin F, Li G, Feng X, Wang K, Sun S.
3. Antihyperglycemic, hypolipidemic and antioxidant activities of total saponins extracted from Aralia taibaiensis in experimental type 2 diabetic rats. [J Ethnopharmacol. 2014 Mar 28]
Author: Weng Y, Yu L, Cui J, Zhu YR, Guo C, Wei G, Duan JL, Yin Y, Guan Y, Wang YH, Yang ZF, Xi MM, Wen AD.
4. Quillaja brasiliensis saponins are less toxic than Quil A and have similar properties when used as an adjuvant for a viral antigen preparation. [Vaccine. 2011 Nov 15]
Author: Silveira F, Cibulski SP, Varela AP, Marqués JM, Chabalgoity A, de Costa F, Yendo AC, Gosmann G, Roehe PM, Fernández C, Ferreira F.