MethylParaben, CAS# 99-76-3, is a organic compound manufactured through chemical synthesis, available as White crystalline powder. Methyl Paraben is widely used as antioxidants. It is widely accepted as safe food additive in many countries.
MethylParaben may increase chance of breast cancer in women.
Ingestion of Methyl Paraben in large quantity may hurt our health, please follow the guideline of using Methyl Paraben: ADI 0-10 mg/kg bw
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Methyl Paraben could have any negative effects on these vulnerable groups. It should be safe to use Methyl Paraben in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Methyl Paraben for long period in food for newborns or pregnant.
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Methyl Paraben is considered safe by FDA according to existing data and granted GRAS status.
No breaking news or public health crises reported about Methyl Paraben reported up to now.
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1. Four Polymorphs of Methyl Paraben: Structural Relationships and Relative Energy Differences. [Cryst Growth Des. 2013 Mar 6]
Author: Gelbrich T, Braun DE, Ellern A, Griesser UJ.
2. Crystal engineering of pharmaceutical Co-crystals: application of methyl paraben as molecular hook. [J Am Chem Soc. 2010 Apr 14]
Author: Khan M, Enkelmann V, Brunklaus G.
3. Mechanism of enhanced dermal permeation of 4-cyanophenol and methyl paraben from saturated aqueous solutions containing both solutes. [Skin Pharmacol Physiol. 2010]
Author: Romonchuk WJ.
4. Combined activation of methyl paraben by light irradiation and esterase metabolism toward oxidative DNA damage. [Chem Res Toxicol. 2008 Aug]
Author: Okamoto Y, Hayashi T, Matsunami S, Ueda K, Kojima N.
5. Simultaneous identification and quantification by liquid chromatography of benzethonium chloride, methyl paraben and triclosan in commercial products labeled as grapefruit seed extract. [Pharmazie. 2007 Aug]
Author: Avula B, Dentali S, Khan IA.